Tuesday, March 1, 2016

ZMapp promising treatment for Ebola – new study



A study released last week has indicated that the experimental Ebola treatment ZMapp has promising potential in treating patients of the deadly viral disease.
The study findings show that the drug sharply increases the chance of surviving virus, according to details released at last week’s medical conference in the US.
ZMapp was one of about half a dozen experimental drugs deployed during the epidemic for trial. But researchers were frustrated by dwindling cases when the epidemic halted so that there weren’t enough patients to administer drugs on.
The ZMapp study involves 72 patients, out of the 200 originally planned. It found that 22 percent of participants given ZMapp died, compared
with 37 percent of participants receiving standard treatments.
But researchers say because so few people were tested, the results could have occurred by chance. Nonetheless the US National Institute of Allergy and Infectious Diseases, which is a co-sponsor of the study, described the drug as "well tolerated and showed promise."
ZMapp is a combination of three genetically engineered antibodies — substances that help direct the immune system's attack on invading germs. The antibodies were produced from tobacco plants.
The drug was developed by Mapp Biopharmaceuticals.
And the US Food and Drug Administration has reportedly cleared the manufacturer to make its drug available to any future patients as needed.
"Having a therapeutic option available for Ebola will help motivate patients to come to treatment units, reducing opportunities for infection in the community," Dr. Armand Sprecher of Doctors Without Borders was quoted saying.
Out of the total participants, majority 54 were from Sierra Leone. 12 were from Guinea, five from Liberia, and One from the US.


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